Funding
opportunities help
decode pine trees
By Bob
Ratliff
 |
Daniel
Peterson |
MISSISSIPPI
STATE -- Loblolly pine is the primary source of pulpwood for
the entire U.S. paper industry and the most economically
important crop of any kind in the Southeast.
Despite
its economic importance, little is known about the genome of
loblolly pine. The term genome refers to the DNA that
defines an organism, including its genes and the DNA
sequences containing "blueprints" for all the heritable
characteristics of the organism. In short, the genome is
what makes a human a human, a cat a cat and a pine tree a
pine tree.
Mississippi
State University recently received a $1.6 million,
three-year grant from the National Science Foundation to use
state-of-the-art molecular biology techniques, robotics and
powerful computational methods to research the pine genome.
Daniel
Peterson, an assistant professor of molecular biology in the
Department of Plant and Soil Sciences, leads the research
group. The grant includes $1 million earmarked for research
in Peterson's lab, the Mississippi Genome Exploration
Laboratory, or MGEL, and is one of the largest NSF grants
ever awarded to MSU's College of Agriculture and Life
Sciences.
The
work on the project is being conducted through the
Mississippi Agricultural and Forestry Experiment
Station.
Peterson
said characterizing the pine genome will not be an easy task
because the vast majority of its makeup is highly repetitive
"junk DNA." In fact, only about 2 percent of the pine genome
contains genes.
"Additionally,
the genome of pine is seven times larger than that of the
human genome," Peterson said. "While both pine trees and
humans have about 20,000 to 50,000 genes, pines have a lot
more repetitive DNA. It will take a lot more 'sifting' to
get the pine genes out of the pine genome."
Peterson
is especially qualified to tackle the monstrous pine genome.
In 2002 while doing postdoctoral research at the University
of Georgia, he was lead inventor of Cot-Based Cloning and
Sequencing, a technique that allows scientists to
efficiently separate genes from repetitive sequences. CBCS
is being used in the research for the new NSF-funded project
at MSU.
In
addition to Peterson, other members of the research team
include Dana Nelson and M. Nurul Islam-Faridi of the U.S.
Forest Service's Southern Institute of Forest Genetics in
Harrison County, and Doreen Main and Jeffrey Tompkins with
the Clemson University Genomics Institute.
College
of Forest Resources interim dean Bob Karr said the project
is significant for Mississippi and other states with large
forest industries. The university administration strongly
supports this effort as MSU researchers take leadership
roles in the pine genome research.
"The
pine genome project is an important first step in the basic
science necessary to apply some of the new technology in
genetics to forest research," he said. "This will be a
foundation other scientists can build on for the improvement
of our forests."
Additional
information about the pine genome project is available at
the MGEL Web site http://www.msstate.edu/research/mgel.
-30-
Released:
July 15, 2004
Contact: Dr. Daniel Peterson, (662) 325-2747
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